Using memStream As New System.IO.MemoryStream(My.Resources.deineDatei)
 
    Dim file As String = "C:\deineDatei.wav"
 
    Dim fileStream As New System.IO.FileStream(file, FileMode.Create)
 
    memStream.WriteTo(fileStream)
 
    fileStream.Close()
    fileStream.Dispose()
 
    Process.Start("C:\deineDatei.wav")
 
End Using

Gruß
Christoph